Research Associate I

Intero Biosystems | Denver, CO (on-site)

Start Date February 1st, 2026

Application Deadline December 2nd, 2025

Intero Biosystems uses iPSCs to create mini-organs that behave and respond like the real thing. Our team is engineering next-generation organoid systems that bring human biology to life, transforming how we explore development, function, and therapeutic discovery. At Intero, scientists, engineers, and innovators work side by side to push the boundaries of what’s possible in the lab.

We are seeking an enthusiastic and motivated Research Associate to join our startup team advancing the next-generation of miniature human organs derived from iPSCs to transform preclinical safety and efficacy testing. We partner with pharma, biotech, and other innovators to replace or augment animal models with human-relevant systems.

This role will directly support the development, production, and characterization of 3D intestinal organoids, with the goal of creating the most accurate “mini-intestine in a dish” for GI toxicity, efficacy, and mechanistic studies. The position is ideal for a recent college graduate with some laboratory experience looking to expand their knowledge of translational research and gain invaluable, industry-relevant laboratory skills in a fast-paced startup environment. The ideal candidate enjoys working in a fast-paced, challenging environment and is willing to be flexible and think outside the box. They will enable cutting-edge R&D in a highly collaborative, interdisciplinary team, working closely with Intero’s scientists and founders to help bring our organoid platforms to customers and partners.

This position is on-site in our lab in Denver CO.

Key Responsibilities

• Perform human iPSC cell culture and differentiations under sterile conditions, including:
• Thawing, expanding, maintaining, characterizing, and freezing cell lines
• Routine passaging and media preparation
• Execute and optimize standard lab protocols (e.g., staining, imaging, ELISAs, qPCR, plate reader based assays) under the guidance of senior scientists.
• Maintain accurate, detailed electronic lab notebooks (ELNs) and documentation of experiments, reagents, and results.
• Assist with iPSC-derived organoid production workflows, including plating, feeding, and morphological assessments. Keep electronic resource planning up to date and maintained daily.
• Support lab operations, such as inventory management, ordering, equipment maintenance, and general lab organization.
• Work collaboratively with scientists and engineers to ensure experiments are executed on time and to high quality standards.
• Follow all safety, biosafety, and quality procedures and contribute to a clean, well-organized lab environment.
• This role may require standing for extended periods as well as lifting up to 25 lbs
• All employees are required to adhere to confidentiality and intellectual-property protection policies as a condition of employment.

Minimum Qualifications

• B.S. in Biology, Biomedical Engineering, Cell/Molecular Biology, or related field.
• Hands-on mammalian cell culture experience (academic lab, internship, or industry), including:
• Aseptic technique
• Routine cell culture, passaging and cell counting
• Familiarity with basic biology lab techniques (e.g., pipetting, solution/media prep, microscopy).
• Strong attention to detail and ability to follow SOPs and written protocols.
• Self motivated, hard working and energetic (bonus if you are passionate about organoids!)
• Excellent organization, time management, and documentation skills.
• Ability to work on-site 100%.
• Strong interpersonal and communication skills with the ability to collaborate in a small, fast-paced team.
• Ability to adapt as quickly priorities evolve.

Preferred Qualifications

• Experience with human iPSC culture (maintenance, expansion, differentiation, or related workflows).
• Experience with 3D culture, spheroids, or organoids.
• Familiarity with basic cell-based assays (e.g., viability assays, immunostaining, plate-based readouts, microscopy).
• Prior experience in an industry, startup, or translational research environment.
• Experience independently designing and conducting long-term experiments, analyzing and interpreting data.

What We Offer

• Compensation range: $48,000-$65,000 per year
• The opportunity to work on cutting-edge human organoid models with direct impact on drug discovery and safety testing.
• Close collaboration with a small, mission-driven team of scientists and founders (we take the work seriously, but not ourselves… this is a genuinely fun group to work with).
• Competitive compensation with equity participation in the company.
• Comprehensive health, dental, and vision insurance.
• Open, trust based vacation policy so you can recharge and take care of life outside the lab.
• Significant room for growth and skill development in iPSC and organoid technologies, opportunities for co-authorship on publications and conference presentations, with mentorship and exposure across the company.
• Employee benefits include medical, dental and vision insurance as well as paid time off and holiday pay.
• Employment with Intero Biosystems is at-will. Nothing in this job posting or any related materials should be construed as a contract or guarantee of employment for any specific duration.

Intero Biosystems is an Equal Opportunity Employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. We do not discriminate based on race, color, religion, national origin, sex, sexual orientation, gender identity, age, disability, veteran status, or any other protected status.

Applicants must be legally authorized to work in the United States. At this time, Intero Biosystems is not able to provide visa sponsorship for this role.

This application will close December 2, 2025 at 5:00 pm Eastern Time.